Spatially coherent modeling of 3D FDG-PET data for assessment of intratumoral heterogeneity and uptake gradients.

Radiomics have become invaluable for non-invasive cancer patient risk prediction, and the community now turns to exogenous assessment, e.g., from genomics, for interpretability of these agnostic analyses.

Predictors of F-DCFPyL PET/CT Positivity in Patients with Biochemical Recurrence of Prostate Cancer After Local Therapy.

Our objective was to investigate the factors predicting scan positivity and disease location in patients with biochemical recurrence (BCR) of prostate cancer (PCa) after primary local therapy using prostate-specific membrane antigen-targeted F-DCFPyL PET/CT. This was a 2-institution study including 245 BCR PCa patients after primary local therapy and negative results on conventional imaging. The patients underwent F-DCFPyL PET/CT.