Publications by authors named "J F Di Cristina"
The interaction between dietary bioactive compounds and mycotoxins in food safety is crucial due to the potential health risks raised by mycotoxins and the protective functions of bioactive substances. This study is focused on red beetroot (Beta vulgaris), a rich source of polyphenols and betalains, incorporated into a daily consumption food such as bread, to examine its effects on the bioavailability of mycotoxins using an in vitro Caco-2 cell model. This study investigates how these compounds affect the bioavailability of mycotoxins, specifically ochratoxin A (OTA), aflatoxin B1 (AFB1), and zearalenone (ZEA), which are known to compromise intestinal barrier function and nutrient absorption.
View Article and Find Full Text PDFUnexpected Delayed Incursion of Highly Pathogenic Avian Influenza H5N1 (Clade 2.3.4.4b) Into the Antarctic Region.
Influenza Other Respir Viruses
October 2024
The current highly pathogenic avian influenza H5N1 panzootic is having substantial impacts on wild birds and marine mammals. Following major and widespread outbreaks in South America, an incursion to Antarctica occurred late in the austral summer of 2023/2024 and was confined to the region of the Antarctic Peninsula. To infer potential underlying processes, we compiled H5N1 surveillance data from Antarctica and sub-Antarctic Islands prior to the first confirmed cases.
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- * Detailed genetic analysis of HPIAV from pinnipeds shows multiple instances of transmission from birds to these marine mammals, indicating the virus's ability to spread across species.
- * The study found that H5N1 strains from pinnipeds in Europe and South America have distinct genetic lineages, suggesting varied evolutionary paths, and highlighted genetic changes that may enhance the virus's ability to infect mammals.
Article Synopsis
- - Hepatitis C virus (HCV) is a major global health issue with millions affected, complicated by the absence of an effective vaccine and ongoing challenges in diagnosis and treatment despite available antiviral therapies.
- - The study investigates HCV's genetic diversity, particularly focusing on mixed infections and the discovery of inter-genotypic recombination between genotypes 1a and 3a in the conserved internal ribosome entry site (IRES) region, which was previously considered rare.
- - Utilizing advanced methods like deep sequencing, the research confirms mixed infections and uncovers new recombinant forms, providing insights into HCV's evolution and adaptation that could inform future treatment strategies.
Phylogenetic analysis reveals that the H5N1 avian influenza A outbreak in poultry in Ecuador in November 2022 is associated with the highly pathogenic clade 2.3.4.4b.
Int J Infect Dis
August 2023
The ongoing H5N1 outbreak in the Americas caused by clade 2.3.4.
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