Publications by authors named "J F Deniset"
Article Synopsis
- Human pericardial fluid (PF) contains biologically active markers that have significant effects on heart-related cellular activities.
- PF can enhance the activity of cardiac fibroblasts, which are important for heart tissue repair, through a specific biological pathway known as the transforming growth factor-β pathway.
- In patients with coronary artery disease, the PF possesses a higher capacity to promote fibrosis compared to those without the disease, indicating a potential area for clinical attention.
Background: Pericardial fluid (PF) contains cells, proteins, and inflammatory mediators, such as cytokines, chemokines, growth factors, and matrix metalloproteinases. To date, we lack an adequate understanding of the inflammatory response that acute injury elicits in the pericardial space.
Objective: To characterize the inflammatory profile in the pericardial space acutely after ischemia/reperfusion.
Tit for TAK1: Reciprocal Regulation of Inflammasome Signaling in Cardiac Hypertrophy.
JACC Basic Transl Sci
December 2023