Publications by authors named "J F Canosa"
Article Synopsis
- The study presents the fifth known case of candida dubliniensis meningitis in an immunocompetent young woman, highlighting a possible link between prior extracorporeal membrane oxygenation (ECMO) and fungal colonization.
- A 22-year-old female initially diagnosed with bacterial meningitis had a history of ECMO treatment during a severe Covid-19 illness, leading to persistent headaches and a complicated diagnosis.
- After extensive testing, including lumbar punctures and MRI scans, her cerebrospinal fluid tested positive for C. dubliniensis, prompting treatment with specific antifungal medications.*
Vitiligo is a common chronic autoimmune disease characterized by white macules and patches of the skin, having a negative impact on patients' life and without any definitive cure at present. Identification of new compounds to reverse depigmentation is therefore a pressing need for this disease. The pharmacologic compounds phosphodiesterase-4 inhibitors (PDE4is) are small molecules with immunomodulatory properties used for treatment of inflammatory dermatoses.
View Article and Find Full Text PDFResearch towards efficient and environmentally friendly thermoelectrics proposes silicon nanostructures as possible candidates through reduction of the phononic thermal conductivity. However, there is scarce literature about experimental measurements of the thermoelectric figure-of-merit on actual crystalline silicon devices. This article reports on the fabrication and full thermoelectric characterization of crystalline 60 nm thick membranes.
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- * Participants who received crisaborole showed a statistically significant greater ability to maintain their skin improvement, particularly during weeks 4 to 36 of the study.
- * Overall, the treatment was effective in both adults and children, with fewer flare occurrences in those taking crisaborole and a similar duration of flare periods compared to the vehicle group.
Atopic dermatitis (AD) is a chronic, relapsing immunoinflammatory skin condition characterized by sensations such as pruritis, pain, and neuronal hypersensitivity. The mechanisms underlying these sensations are multifactorial and involve complex crosstalk among several cutaneous components. This review explores the role these components play in the pathophysiology of atopic dermatitis.
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