Publications by authors named "J F Burr"

Induction of senescence by chemotherapeutic agents arrests cancer cells and activates immune surveillance responses to contribute to therapy outcomes. In this investigation, we searched for ways to enhance the NK-mediated elimination of senescent cells. We used a staggered screen approach, first identifying siRNAs potentiating the secretion of immunomodulatory cytokines to later test for their ability to enhance NK-mediated killing of senescent cells.

View Article and Find Full Text PDF

High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the immediate cardiovascular effects of different cannabis inhalation methods and cannabinoid profiles, focusing on THC and CBD.
  • Researchers assessed arterial stiffness, endothelial function, and cardiac performance in 22 healthy cannabis users before and after using THC-dominant and CBD-dominant strains.
  • Results show that THC use significantly increases heart rate and blood pressure, while CBD does not affect these cardiovascular markers, indicating potential risks associated with THC consumption.
View Article and Find Full Text PDF

This study examined the association between COVID-19 concerns and depression among adults in later life. We also examined whether race/ethnic status moderated this relationship. This study used data from the 2020 Using the 8-item CES-D scale, we defined probable depression as having three or more depressive symptoms.

View Article and Find Full Text PDF