Publications by authors named "J F Brouet"
Article Synopsis
- Neutrophilic dermatoses are skin inflammatory disorders linked to conditions like autoimmune diseases and myeloproliferative disorders, with limited knowledge about their relationship with monoclonal immunoglobulin (MIg).
- The study analyzed 26 patients with neutrophilic dermatoses associated with MIg, examining clinical and biological factors, including cytokines and adhesion molecules.
- Findings indicate a significant link between IgA isotype MIg and neutrophilic dermatoses, revealing a unique inflammatory profile marked by elevated levels of specific molecules.
This retrospective analysis was conducted in 64 patients diagnosed with type I cryoglobulinaemia (CG) followed at two French centres. Median follow-up was 6·75 years. CG was IgG in 60% and IgM in 40% of all cases and was asymptomatic in 16 patients (25%).
View Article and Find Full Text PDFSchnitzler syndrome is a rare plasma cell disorder the pathogenesis of which is still not fully understood. We evaluated the circulating levels of four major angiogenic cytokines (VEGF, angiogenin, angiopoietin-1 and angiopoietin-2) and six bone remodeling markers (sRANKL, osteoprotegerin, dickkopf-1, CTX, osteocalcin and bone-specific alkaline phosphatase-bALP) in 13 patients with Schnitzler syndrome. At diagnosis, patients had elevated angiogenic cytokines.
View Article and Find Full Text PDFXanthomas are a common manifestation of lipid metabolism disorders. They include hyperlipemic xanthoma, normolipemic xanthoma, and a related condition, necrobiotic xanthogranuloma (NXG). All 3 forms can be associated with monoclonal immunoglobulin (MIg).
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