Optimizing drought tolerance in cassava through genomic selection.

The complexity of selecting for drought tolerance in cassava, influenced by multiple factors, demands innovative approaches to plant selection. This study aimed to identify cassava clones with tolerance to water stress by employing truncated selection and selection based on genomic values for population improvement and genotype evaluation . The Best Linear Unbiased Predictions (BLUPs), Genomic Estimated Breeding Values (GEBVs), and Genomic Estimated Genotypic Values (GETGVs) were obtained based on different prediction models via genomic selection.

[Metoposcopy].

From the oracle of Delphi to magnetic resonance imaging, the anatomist's dissecting gaze has always been accompanied by a connective reading, nourishing subjectivity. The face offered to view has thus been the subject since Aristotle (and probably before without any written record of it being kept) of multiple interpretations, becoming a standard throughout the ages. A whole vocabulary emanates from it: metoposcopy, prosopology, physiognomony, phrenology, organology, morphopsychology, amphibology… which punctuated the beyond of the gaze.

Signal detection of drugs associated with obstructive and central sleep apnoea.

We aim to discover new safety signals of drug-induced sleep apnoea (SA), a global health problem affecting approximately 1 billion people worldwide. We first conducted a series of sequence symmetry analyses (SSA) in a cohort composed from all patients who received a first SA diagnosis or treatment between 2006 and 2018 in the Echantillon Généraliste des Bénéficaires (EGB), a random sample of the French healthcare database. We used two primary outcomes to estimate the sequence ratio (SR) for all drug classes available in France: a sensitive one (diagnosis or treatment of SA) and a specific one (Positive Airway Pressure (PAP) therapy).

Mask side-effects are related to gender in long-term CPAP: results from the InterfaceVent real-life study.

Background: Over the past three decades, our understanding of sleep apnea in women has advanced, revealing disparities in pathophysiology, diagnosis, and treatment compared to men. However, no real-life study to date has explored the relationship between mask-related side effects (MRSEs) and gender in the context of long-term CPAP.

Methods: The InterfaceVent-CPAP study is a prospective real-life cross-sectional study conducted in an apneic adult cohort undergoing at least 3 months of CPAP with unrestricted mask-access (34 different masks, no gender specific mask series).

Molecular Hydrogen for Outpatients with COVID-19 (Hydro-COVID): A Phase 3 Randomised, Triple-Blinded, Pragmatic, Placebo-Controlled, Multicentre Trial.

. Due to its antioxidant, anti-inflammatory, anti-apoptosis, and anti-fatigue properties, molecular hydrogen (H) is potentially a novel therapeutic nutrient for patients with coronavirus acute disease 2019 (COVID-19). We determined the efficacy and safety profile of hydrogen-rich water (HRW) to reduce the risk of COVID-19 progression.