Fish microglia: Beyond the resident macrophages of the central nervous system - A review of their morphofunctional characteristics.

From classical to modern literature on microglia, the importance of the potential and variability of these immune cells in vertebrates has been pointed out. Recent aspects such as relationships and interactions between microglia and neurons in both normal and injured neural tissues, as well as their nexus with other organs and with the microbiota, or how these cells are modulated during development and adulthood are current topics of major interest. State-of-the-art research methodologies, including microscopy and potent in vivo imaging techniques, genomic and proteomic methods, current culture conditions together with the easy maintenance and manipulation of some fish embryos and adult specimens such as zebrafish (Danio rerio), have emerged and adapted to the phylogenetic position of some fish species.

Impact of gender on in-hospital and long-term outcomes after transcatheter aortic valve implantation: an analysis of the Spanish TAVI registry.

Introduction And Objectives: Impact of gender on long-term outcomes after transcatheter aortic valve implantation (TAVI) remains uncertain. We aimed to investigate gender-specific differences in TAVI and its impact on outcomes.

Methods: This analysis used data from the prospective Spanish TAVI registry, which included consecutive TAVI patients treated in 46 Spanish centers from 2009 to 2021.

Control-oriented quality modelling approach of sewer networks.

A control-oriented quality modeling approach is proposed for sewer networks, which can represent quality dynamics using simple equations in order to optimize pollution load from combined sewer overflows in large scale sewer network in real time. Total suspended solid has been selected as the quality indicator, regarding it is easy to be estimated through measuring turbidity and correlated with other quality indicators. The model equations are independent for different elements in sewer network, which allows a scalable usage.

Integrated pollution-based real-time control of sanitation systems.

An integrated pollution-based real-time control (RTC) approach is proposed for a sewer network (SN) integrated with wastewater treatment plants (WWTPs) in a sanitation system (SS) to mitigate the impacts of pollution from combined sewer overflows (CSOs) on ecosystems. To obtain the optimal solution for the SS while considering both quantity and quality dynamics for multiple objectives, model predictive control (MPC) is selected as the optimal control method. To integrate SN and WWTP management, a feedback coordination algorithm is developed.