Publications by authors named "J F Arena"
The neuropathological basis of elevated serum neurofilament light following experimental concussion.
Acta Neuropathol Commun
December 2024
Article Synopsis
- The diagnosis of mTBI primarily relies on clinical symptoms and neuroimaging, but predicting poor recovery outcomes remains difficult due to a lack of early objective testing.
- Recent research suggests that measuring the neurofilament light (NfL) protein in the serum may serve as a promising biomarker for assessing mTBI and that disruptions in the blood-brain barrier may play a key role in NfL dynamics.
Objective: Fractures of the atlas are typically considered stable or unstable based on the integrity of the transverse ligament. Whereas stable Jefferson burst fractures can be treated nonoperatively, unstable fractures with disruption of the transverse ligament often require surgical intervention. Atlas osteosynthesis has been proposed as a motion-preserving alternative to atlantoaxial fusion.
View Article and Find Full Text PDFObjective: Surgical correction of adult spinal deformity (ASD) is associated with a high rate of hardware complication that can be challenging to predict. Hardware integrity and alignment after surgery are typically followed with standing radiography, where pedicle screw loosening may be incidentally identified but the clinical significance of which is often unclear. This study aimed to identify the incidence and implications of pedicle screw loosening at the upper instrumented vertebra (UIV) after surgical correction of ASD.
View Article and Find Full Text PDFPurpose: This study aimed to investigate the relationship of preoperative hemoglobin levels as an independent prognostic factor for hospital and intensive care unit (ICU) length of stay (LOS) in patients undergoing surgery for adult spinal deformity (ASD), with the intent of determining whether there exists a correlation and enhancing patient preoperative optimization protocols.
Methods: The authors reviewed consecutive patients who underwent elective thoracolumbosacral posterior spinal fusion (PSF) involving six or more vertebrae for ASD from January 1, 2013, to December 13, 2021, with a minimum follow-up period of two years. This study primarily investigated the association of preoperative hemoglobin levels with hospital and ICU LOS.