Publications by authors named "J F Aloia"
Background: A 2017 meta-analysis of data from 25 randomised controlled trials (RCTs) of vitamin D supplementation for the prevention of acute respiratory infections (ARIs) revealed a protective effect of this intervention. We aimed to examine the link between vitamin D supplementation and prevention of ARIs in an updated meta-analysis.
Methods: For this systematic review and meta-analysis, we searched MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, and the ClinicalTrials.
Article Synopsis
- A 2017 meta-analysis indicated that vitamin D supplementation might protect against acute respiratory infections (ARIs), leading to further research with 20 additional randomized controlled trials (RCTs) since then.
- A systematic review and meta-analysis was conducted, analyzing data from 45 eligible RCTs involving over 73,000 participants to evaluate the efficacy of vitamin D in preventing ARIs.
- The findings showed that vitamin D supplementation reduced the risk of ARIs overall, particularly when given daily, in moderate doses (400-1000 IU), and for periods shorter than 12 months, although no significant differences were found based on initial vitamin D levels.