Publications by authors named "J Ernest Minton"
Article Synopsis
- Seventeen percent of the UK population are migrants, and while they generally have better overall mortality rates, they face higher deaths from certain causes like infectious diseases.
- A study conducted in England and Wales during 2020-2021 found that most migrants had higher mortality rates from COVID-19 compared to non-migrants, particularly those from Bangladesh, Pakistan, and the Caribbean.
- The findings highlight the need for policymakers to consider migration status in data collection to better understand and address health inequalities among different populations.
Voltage-gated sodium channel β1 subunits are essential proteins that regulate excitability. They modulate sodium and potassium currents, function as cell adhesion molecules and regulate gene transcription following regulated intramembrane proteolysis. Biallelic pathogenic variants in , encoding β1, are linked to developmental and epileptic encephalopathy 52, with clinical features overlapping Dravet syndrome.
View Article and Find Full Text PDFObjectives: The number of deaths occurring in private homes in England and Wales had been rising for years, increasingly rapidly from 2020. Media stories and research linked decomposing bodies found in private homes with pandemic-related social isolation. We aim to explore whether these incidents are one-offs or part of a wider trend.
View Article and Find Full Text PDFLife expectancy, healthy life expectancy, and inequalities in Hong Kong, 2007-2020.
Lancet Reg Health West Pac
December 2023
Article Synopsis
- The NVX-CoV2373 vaccine, developed by Novavax, demonstrated safety and a strong immune response in early studies, but further research was needed to confirm its efficacy and safety in a larger population.
- In a phase 3 trial with over 15,000 participants in the UK, adults received two doses of either the vaccine or a placebo, with results showing a vaccine efficacy of 89.7% against COVID-19 infections and no severe cases among those vaccinated.
- The vaccine appeared effective against variants, with high efficacy rates against the B.1.1.7 variant, and adverse reactions were generally mild, indicating a favorable safety profile.