Publications by authors named "J Ermer"
Background: Implementation of a successful night curriculum has been a historical barrier to education during night rotations. Residents are tasked with teaching students and peers at night, often with little educational material to support this. To address the need for engaging night curriculum for pediatric residents, we aimed to (1) develop and implement a night curriculum with an emphasis on residents as teachers (RaTs) and (2) explore residents' experience with the RaT curriculum through a secondary qualitative analysis of reflections.
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- The study aimed to understand how certain tiny molecules called microRNAs (miRNAs) are connected to a condition called Primary Hyperparathyroidism (PHPT), which affects bones.
- They looked at women who have PHPT and compared their miRNA levels to women who do not have this condition.
- The researchers found 9 specific miRNAs that were different in people with PHPT, and these were linked to parathyroid hormone levels, which plays a role in how bones are remodeled, but they did not strongly relate to bone density.
The analytical procedure life cycle (APLC) provides a holistic framework to ensure analytical procedure fitness for purpose. USP's general chapter <1220> considers the validation activities that take place across the entire analytical procedure lifecycle and provides a three-stage framework for its implementation. Performing ongoing analytical procedure performance verification (OPPV) (stage 3) ensures that the procedure remains in a state of control across its lifecycle of use post validation (qualification) and involves an ongoing program to collect and analyze data that relate to the performance of the procedure.
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- - Platelets, which are special blood cells without a nucleus, have mitochondria that help them regulate blood clotting after an injury, but the relationship between mitochondrial and nuclear gene expression is not fully understood.
- - Researchers deleted specific genes (Elac2, Ptcd1, or Mtif3) in platelets to study their roles in mitochondrial gene expression and found that this led to increased platelet production and issues like lower platelet counts and longer bleeding times.
- - Analysis of genes and proteins showed that proper mitochondrial gene expression is crucial for platelet function, particularly in processes like blood coagulation and healing after injury.