Screen media use, and particularly mobile device use, is frequent among preschool-age children. Studies support that problematic media use (PMU) symptoms are present among older children (4-11-year-olds) and toddlers, and PMU correlates with child temperament and parenting around child media use. We examined the performance of a widely used PMU measure among a sample of 85 3-5-year-old children to document whether variation in PMU exists in this age group and whether this PMU measure specifically has face validity relative to expected correlates of PMU.
View Article and Find Full Text PDFAm J Transplant
November 2024
Immunosuppression can be withdrawn from selected liver transplant recipients, although robust clinical predictors of tolerance remain elusive. The Immune Tolerance Network ITN056ST study (OPTIMAL; NCT02533180) assessed clinical outcomes and mechanistic correlates of phased immunosuppression withdrawal (ISW) in nonautoimmune, nonviral adult liver transplant recipients. Enrolled subjects were ≥3 years posttransplant with minimal/absent inflammation or fibrosis on a screening liver biopsy.
View Article and Find Full Text PDFLiving donor liver transplantation (LDLT) was first performed in the US in 1989, primarily benefiting pediatric patients. Its adoption for adults faced setbacks after a donor death in 2001, causing widespread risk aversion. Despite ethical justification and demonstrated safety, LDLT remains underutilized, with fewer than 10% of liver transplants being LDLT.
View Article and Find Full Text PDFObjective: The objective of this study is to evaluate obesity-related genetic factors in relation to excess consumption and assess if food cues modify associations.
Methods: Children (9-12 years) completed a randomized crossover experiment. During two visits, children ate a preload and then snacks ad libitum while watching television, embedded with food or non-food advertisements to assess eating in the absence of hunger (EAH).