Test-takers' perspectives on consumer genetic testing for hereditary cancer risk.

Purpose: With few exceptions, research on consumer genetic testing for hereditary cancer risk has focused on tests with limited predictive value and clinical utility. Our study advances the existing literature by exploring the experiences and behaviors of individuals who have taken modern consumer genetic tests for cancer susceptibility that, unlike earlier tests, screen for medically significant variants.

Methods: We interviewed 30 individuals who had undergone consumer genetic testing for hereditary cancer risk between 2014 and 2019.

Slip versus Slop: A Head-to-Head Comparison of UV-Protective Clothing to Sunscreen.

Ultraviolet radiation (UVR) exposure is the most important modifiable risk factor for skin cancer development. Although sunscreen and sun-protective clothing are essential tools to minimize UVR exposure, few studies have compared the two modalities head-to-head. This study evaluates the UV-protective capacity of four modern, sun-protective textiles and two broad-spectrum, organic sunscreens ( 30 and 50).

A Performance Management System for Long-Term Germplasm Conservation in CGIAR Genebanks: Aiming for Quality, Efficiency and Improvement.

UN Sustainable Development Goal 2 Target 2.5 focuses on the conservation of genetic diversity in soundly managed genebanks. In examining the term "soundly managed", it becomes quickly evident that there is much more to long-term conservation than placing samples of seeds or other germplasm in long-term conservation conditions.

MUNIn: A statistical framework for identifying long-range chromatin interactions from multiple samples.

Chromatin spatial organization (interactome) plays a critical role in genome function. Deep understanding of chromatin interactome can shed insights into transcriptional regulation mechanisms and human disease pathology. One essential task in the analysis of chromatin interactomic data is to identify long-range chromatin interactions.

Regional versus local wind speed and direction at a narrow beach with a high and steep foredune.

Dune growth and post-storm recovery of foredune systems is predominantly determined by the aeolian sand transport through the beach-dune interface. Potential sand transport rates, estimated with empirical transport equations using regionally representative wind conditions, are generally too high. This positive bias might be, at least partly, due to the effect of the beach and foredune topography on the regional airflow.