Publications by authors named "J Eid Fares"

Article Synopsis
  • Recent advancements in neuroimaging and machine learning have enhanced the diagnosis of IDH-wildtype glioblastoma, which is vital due to the disease's complexity.
  • Techniques like diffusion tensor imaging and magnetic resonance radiomics provide noninvasive insights into tumor characteristics, aiding in diagnosis and prognosis.
  • The integration of these technologies with machine learning can lead to the development of image-based biomarkers, allowing for personalized treatment approaches while minimizing the need for invasive procedures.
View Article and Find Full Text PDF

ETx-22, a novel ADC combining a tumor nectin-4-specific antibody and an innovative linker to exatecan, demonstrates significant and durable responses in low-target-expressing tumor models that are resistant to MMAE-based EV and has a better toxicity profile. This new ADC has the potential to benefit additional patient populations beyond its current indication.

View Article and Find Full Text PDF
Article Synopsis
  • * A literature review investigates genetic and pathogenic factors contributing to both idiopathic and adult degenerative scoliosis, examining their complex origins and mechanisms through data sourced from PubMed and Google Scholar.
  • * The research categorizes genetic influences on idiopathic scoliosis and identifies factors like inflammation and hormonal changes in adult degenerative scoliosis, while also outlining current research limitations and suggesting future study directions.
View Article and Find Full Text PDF
Article Synopsis
  • The review explores how museum and art gallery activities impact the wellbeing of individuals recovering from drug addiction, patients with dementia, and both younger and older adults.
  • A comprehensive search led to the inclusion of 15 original studies from 2013-2023 that focused on these effects, demonstrating positive health outcomes for those with chronic mental and physical diseases.
  • The findings suggest that art-based interventions in museums can be beneficial as non-medical treatments for mental health issues and can enhance the overall wellbeing of various age groups.
View Article and Find Full Text PDF

Background: Sarcoidosis is a multisystem inflammatory disease in which management and outcomes can vary widely. The renin-angiotensin-aldosterone system (RAAS) has been implicated in its pathogenesis, yet the impact of RAAS modulators on health outcomes in sarcoidosis remains poorly understood.

Research Question: How do pharmacologic modulators of RAAS affect health outcomes in patients with a diagnosis of sarcoidosis?.

View Article and Find Full Text PDF