Publications by authors named "J Eduardo Villarreal Barajas"
Article Synopsis
- Tandem duplications (TDs) in the UBTF gene are a recently identified genetic alteration linked to pediatric and adult acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), establishing UBTF-TD as a distinct subtype of AML.
- A study of 27 pediatric patients revealed that UBTF-TD is commonly associated with symptoms like cytopenia and characteristic changes in bone marrow, such as erythroid hyperplasia and trilineage dysplasia.
- The findings suggest that patients with MDS and AML exhibiting UBTF-TD have similar prognoses, indicating that both conditions may represent different manifestations of the same underlying disease.
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Article Synopsis
- This study investigated the relationship between ABO blood types and the risk of postoperative adjacent segment degeneration (ASD) after lumbar spine fusion surgery.
- It included 445 patients with various blood types and assessed factors like spinopelvic alignment, perioperative care, and patient outcomes, finding no significant differences in recovery and complications based on blood type, except for increased epidural hematomas in A+ patients.
- The research concluded that ABO blood type is a non-modifiable risk factor linked to a higher likelihood of developing ASD, particularly in B+ patients, marking a significant first step in understanding this association.
Crimean-Congo hemorrhagic fever virus can cause lethal disease in humans yet there are no approved medical countermeasures. Viral glycoprotein GP38, exclusive to Nairoviridae, is a target of protective antibodies and is a key antigen in preclinical vaccine candidates. Here, we isolate 188 GP38-specific antibodies from human survivors of infection.
View Article and Find Full Text PDFCrimean-Congo hemorrhagic fever virus can cause lethal disease in humans yet there are no approved medical countermeasures. Viral glycoprotein GP38, unique to , is a target of protective antibodies, but extensive mapping of the human antibody response to GP38 has not been previously performed. Here, we isolated 188 GP38-specific antibodies from human survivors of infection.
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