Publications by authors named "J E Thompson"
Background: Massively parallel sequencing (MPS) of nucleic acids has been a transformative technology for basic and applied genomic science, increasing efficiencies and decreasing costs to enable studies of unprecedented scope and impact. In clinical settings, these technological and scientific advances have led to the development of tests that are increasingly fast, comprehensive, and more frequently employed. Practitioners of genomic medicine have applied these tools across clinical settings, including diagnosis of inherited disorders and cancers and infectious disease detection and surveillance.
View Article and Find Full Text PDFBackground: Guidelines for randomised controlled trials (RCTs) recommend reporting relative and absolute measures of effect for binary outcomes while adjusting for covariates. There are a number of different ways covariate-adjusted relative risks and risk differences can be estimated.
Objectives: Our goal was to identify methods used to estimate covariate-adjusted relative risk and risk differences in RCTs published in high-impact journals with binary outcomes.
Article Synopsis
- A team of over 180 researchers from more than 40 countries is addressing the issues related to "phantom agents," which are proposed pathogenic agents that are listed without concrete evidence of their existence.
- These phantom agents, identified only through symptoms and lacking proper isolates or genetic data, create obstacles for trade and plant certification, making effective detection and risk assessment difficult.
- The researchers recommend removing these agents from regulatory lists and updating standards in line with modern diagnostic methods to facilitate germplasm exchange and support global agriculture.