Publications by authors named "J E Sykes"
Article Synopsis
- Testicular cancer is the most common cancer in young adult men, with high survival rates of around 99% for early-stage and over 80% for advanced-stage cases.
- Traditional tumor markers like AFP, β-hCG, and LDH have limited sensitivity and can give false positives, leading to a need for new biomarkers.
- MicroRNA-371a-3p shows promising results in diagnosing germ cell tumors with around 90% sensitivity and may help in treatment decisions, while ongoing clinical trials are validating its effectiveness and exploring other biomarkers like ctDNA and CTCs.
Introduction: Chemoradiotherapy with MRI-guided brachytherapy boosts is the standard of care for locally advanced cervical cancer. Data from the RetroEMBRACE and EMBRACE I trials provide dose-response curves for target volumes and OAR. This study evaluated plan quality, safety and toxicity following escalation of the CTV_HR D90 prescription from 80-90 Gy to 85-95 Gy for two different applicator designs.
View Article and Find Full Text PDFBackground: High-affinity radiohybrid PSMA-targeting radiopharmaceutical F-flotufolastat (F-rhPSMA-7.3) is newly approved for diagnostic imaging of prostate cancer. Here, we conduct a post hoc analysis of two phase 3 studies to quantify F-flotufolastat uptake in a range of normal organs.
View Article and Find Full Text PDFBackground: This study surveyed family medicine residents in North Carolina regarding the state of nutrition education in their residency training. In addition, the survey explored comfort levels with, and attitudes about, discussing nutrition with patients.
Methods: We administered an online questionnaire to family medicine residents in North Carolina (n = 384) asking about their history of nutrition training and their current attitudes about nutrition.
Safety in Rhinoplasty: Avoidance and Management of Complications.
Facial Plast Surg Clin North Am
November 2024
Article Synopsis
- Rhinoplasty is a widely performed cosmetic surgery, but it carries a risk of complications.
- Common complications include scarring, asymmetries, nasal airway issues, and even deformities.
- Understanding these risks and having strategies to prevent and manage them is essential for patient safety and better surgical results.