Publications by authors named "J E Sheehy"

Purpose: Porcine cervical spines are commonly used as a surrogate for human lumbar spines due to their similar anatomic and mechanical characteristics. Despite their use in spinal biomechanics research, porcine annulus fibrosus (AF) yield and ultimate properties have not been fully evaluated. This study sought to provide a novel dataset of elastic, yield, and ultimate properties of the porcine AF loaded in the circumferential direction.

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  • Anxiety and depressive disorders can lead to cognitive control deficits, but the specific brain mechanisms behind this are still unclear.
  • Researchers studied participants with refractory epilepsy to see how anxiety/depression affected their brain and behavior during a cognitive task, using high-resolution EEG.
  • Key findings revealed that those with anxiety/depression took longer to respond under cognitive load but maintained response accuracy, with notable changes in brain activity patterns in regions linked to conflict processing, suggesting increased cognitive resource demands due to inefficient processing.
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Purpose: Understanding how spinal orientation affects injury outcome is essential to understand lumbar injury biomechanics associated with high-rate vertical loading.

Methods: Whole-column human lumbar spines (T12-L5) were dynamically loaded using a drop tower to simulate peak axial forces associated with high-speed aircraft ejections and helicopter crashes. Spines were allowed to maintain natural lordotic curvature for loading, resulting in a range of orientations.

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This study introduces a novel concept of 'Adaptively Stacked' Species Distribution Models (AS-SDMs) to predict blue carbon habitat distribution, abundance, carbon stocks, and carbon sequestration potential in Orkney. AS-SDMs are built from Weighted Boosted Regression Trees (WBRTs) that adaptively stack blue carbon sediment thickness, sediment carbon content, and sequestration potential to predicted abundance. A novel method to describe substrate types by relative inputs of mud, sand, and gravel is detailed that better characterises the determining factors of seagrass, maerl, and horse mussel abundance.

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  • Macrocyclic lactones (MLs) are currently the only licensed drugs for preventing heartworm disease in dogs, effectively killing larvae before they can develop into adult worms.
  • Moxidectin, a specific ML, has notable advantages over other MLs, like longer duration and higher safety for dogs with specific genetic defects, as well as better effectiveness against resistant heartworm strains.
  • Compliance with heartworm prevention is critical, and products like Simparica Trio and injectable moxidectin (ProHeart 6 and ProHeart 12) have shown to improve adherence due to their extended protection and convenience compared to traditional monthly treatments.
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