Child protection concern in patients during the COVID-19 lockdown.

During the COVID-19 lockdown, social isolation from school closures and home visitation restrictions compounded known risk factors for child maltreatment. The aim of our study was to determine the incidence and types of child protection concern (CPC) among inpatients during the COVID-19 lockdown compared to the matched timeframe in 2019. We retrospectively reviewed the CPC assessments performed at Children's Health Ireland at Crumlin and Tallaght from March 13 to August 31, 2020, and the same period in 2019.

Screening with tumor markers: critical issues.

Reviewing the literature it would appear that tumor markers have often flattered to deceive. Early promise does not often seem to be borne out in extended trials. Despite apparently high specificity, very few markers are capable of assisting in a screening process.

Markers of tumor burden : an overview.

Since ancient times, cancer has been known to humankind. The ancient Greeks and Romans have left us with writings in which various treatment options are discussed (1). Disease processes and causes were not well understood, however; the humoral pathology established by the ancient Greeks of the school of Galen in the second century ad was to survive virtually intact until the mid-nineteenth century.