Organophosphate pesticide exposure and neurobehavioral performance in agricultural and non-agricultural Hispanic workers.

Our understanding of the health risks of farmworkers exposed to pesticides in their work and home environments is rapidly increasing, although studies designed to examine the possible neurobehavioral effects of low-level chronic pesticide exposure are limited. We measured dialkyl phosphate urinary metabolite levels, collected environmental dust samples from a subset of homes, obtained information on work practices, and conducted neurobehavioral tests on a sample of farmworkers in Oregon. Significant correlations between urinary methyl metabolite levels and total methyl organophosphate (azinphos-methyl, phosmet, malathion) house dust levels were observed.

Determination of acephate in human urine.

Acephate is a commonly used organophosphate insecticide applied on agricultural crops and in residential communities. Because very little acephate is metabolized prior to excretion, the parent pesticide compound can be measured in human urine. The residue method must be sensitive enough to determine human exposure and potential health risk for both agricultural workers and their families who may be exposed by pesticide drift or by inadvertent carry-home residues.

Neurobehavioral performance in preschool children from agricultural and non-agricultural communities in Oregon and North Carolina.

Organophosphate (OP) pesticides produce acute toxic effects but little is known about low-level chronic exposures. Latino children of agricultural workers have a high risk of exposure to pesticides because of the close proximity of their homes to fields where pesticides are applied and from take-home exposure. Neurobehavioral performance of preschool children from agricultural (AG) communities was compared to performance of those from non-agricultural (Non-AG) communities in Oregon and North Carolina.

Variation in organophosphate pesticide metabolites in urine of children living in agricultural communities.

Children of migrant farmworkers are at increased risk of exposure to organophosphate pesticides because of "carry-home" transport processes and residential location. Although this at-risk status is generally recognized, few available reports describe the extent of this exposure among agricultural communities. We quantified dialkyl phosphate (DAP) levels in serial samples of urine from 176 children, 2-6 years of age, in three Oregon communities hosting differing agricultural industries: pears, cherries, and fruit berries.

Pesticide exposure and self reported home hygiene: practices in agricultural families.

Little is known about environmental exposure to pesticides and the extent to which exposure is affected by drift from agricultural applications and take home exposure from agricultural workers. The study focused on 24 agricultural families in the northwestern United States and measured levels of organophosphate pesticides (OP) in house dust. Pesticide residues were significantly associated with the number of individuals in the home whose work included high exposure pesticide activities.