Publications by authors named "J E Reedy"
Objective: To describe the lived experience of patients with NORSE and explore quality of life (QOL) for patients and their caregivers.
Background: NORSE is a rare condition characterized by refractory status epilepticus, often of unknown cause, in a previously neurologically healthy individual. Febrile infection-related epilepsy syndrome (FIRES) is a subset of NORSE.
Time-restricted eating (TRE) is a type of intermittent fasting (IF). Food can be consumed as desired during the eating period, but not during the remainder of the day. Studies suggest that many of the health benefits of fasting may not simply be the result of weight loss, but also due to the body's responses to the fasting that lead to improved metabolic functioning.
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- - Respiratory fungal infections pose a serious health risk and existing animal models don't accurately mimic human disease, prompting the need for better research models.
- - This study used primary human airway epithelial cells (hAECs) to examine responses to two important fungal pathogens through single-cell RNA sequencing.
- - Findings showed that while both fungi caused cellular stress and inflammation, they impacted different cell types and pathways, highlighting unique stress responses that could lead to potential treatment targets.
Article Synopsis
- A bacteria called pneumococcus can cause pneumonia and can spread from the lungs to the blood, leading to serious illnesses like septicemia and meningitis, which can increase the chances of dying three times more.
- Scientists are looking for new treatments because current vaccines aren't working well against it and some medicines are becoming less effective.
- A substance called HXA made by the bacteria can cause immune cells (PMNs) to move in a way that damages tissues and helps the bacteria spread, so focusing on stopping this process could help fight the disease.
Climate change presents multiple challenges to rural communities. Here, we investigated the toxicological potential of the six types of particulate matter most common to rural Arkansas: soil, road, and agricultural dusts, pollen, traffic exhaust, and particles from biomass burning in human small airway epithelial cells (SAECs). Biomass burning and agricultural dust demonstrated the most potent toxicological responses, exhibited as significant ( < 0.
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