Publications by authors named "J E Pike"
Background: Mild cognitive impairment (MCI) represents a stage between cognitively normal and Alzheimer's disease. Despite much published research on MCI, there continues to be a knowledge gap of volumetric brain changes in MCI versus cognitively normal (CN) in racially diverse, community-based samples.
Objective: The study aimed to understand differences in volume of selected brain regions in individuals with MCI versus those who are cognitively normal.
Objective: The aim of the study is to assess the effect of an emergency department (ED) standardized clinical guideline for adolescent heavy menstrual bleeding on the rate of return ED visits and ED provider history-taking and management of this condition.
Methods: This was a retrospective cohort study. Patients less than 18 years old presenting to a single academic children's hospital ED between 2010 and 2020 with a chief complaint of heavy menstrual bleeding were included.
Article Synopsis
- Respiratory syncytial virus (RSV) leads to significant hospitalizations in infants in the US, prompting recommendations for nirsevimab to prevent RSV in all infants under 8 months and at-risk children up to 19 months during their RSV seasons.* -
- A simulation study found that administering nirsevimab could potentially avoid over 107,000 outpatient visits and 14,000 hospitalizations annually if half of newborns receive it, costing approximately $153,517 per quality-adjusted life year (QALY) saved.* -
- The analysis suggests nirsevimab is cost-effective, particularly for high-risk infants, though the cost-per-QALY can vary widely based on factors like hospitalization costs
Background And Objectives: Respiratory syncytial virus (RSV) commonly causes hospitalization among US infants. A maternal vaccine preventing RSV in infants, RSV bivalent prefusion F maternal vaccine (RSVpreF), was approved by the US Food and Drug Administration and recommended by the Advisory Committee on Immunization Practices. Our objective was to evaluate the health benefits and cost-effectiveness of vaccinating pregnant persons in the United States using RSVpreF.
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