Publications by authors named "J E Mylroie"
The presence of per- and polyfluoroalkyl substances (PFASs) in aquatic environments is often persistent and widespread. Understanding the potential adverse effects from this group of chemicals on aquatic communities allows for better hazard characterization. This study examines impacts on zebrafish () embryo physiology, behavior, and lipid levels from exposure to perfluorooctanoic acid (PFOA), perfluorohexane sulfonate (PFHxS), and heptadecafluorooctanesulfonic acid (PFOS).
View Article and Find Full Text PDFA prior multigenerational perfluorooctane sulfonic acid (PFOS) exposure investigation in zebrafish reported adverse effects at 0.734 µg/L, among the lowest aquatic effect levels for PFOS reported to date. The present three-generation PFOS exposure quantified survival, growth, reproduction, and vitellogenin (VTG; egg yolk protein) responses in zebrafish, incorporating experimental design and procedural improvements relative to the earlier study.
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- * An interdisciplinary group of experts developed a strategic framework for exploring these planetary caves, focusing on areas like astrobiology, geology, and robotics, aiming to guide research for the next decade.
- * They identified 53 priority research questions from an initial list of 198, emphasizing that with sufficient funding and support, advancements in technology could lead to robotic missions investigating lunar and Martian caves for evidence of extraterrestrial life and future human habitation.
Contaminants of Emerging Concern (CECs) can be measured in waters across the United States, including the tributaries of the Great Lakes. The extent to which these contaminants affect gene expression in aquatic wildlife is unclear. This dataset presents the full hepatic transcriptomes of laboratory-reared fathead minnows (Pimephales promelas) caged at multiple sites within the Milwaukee Estuary Area of Concern and control sites.
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- The evaluation of chemicals using early-life stage zebrafish has shown significant variation in reported phenotypes among researchers, highlighting the need for consistent terminology and data standards in toxicological studies.
- By applying standardized phenotype terminology via the Zebrafish Phenotype Ontology, a recent study found that data consistency improved and ambiguity decreased when researchers analyzed zebrafish larvae for malformations.
- A larger-scale study is needed to confirm these findings, but establishing a common data standard is recommended to enhance agreement and repeatability across different laboratories, paving the way for a zebrafish phenotype atlas.