Publications by authors named "J E Morley"
Humans show an impressive ability to plan over complex situations and environments. A classic approach to explaining such planning has been tree-search algorithms which search through alternative state sequences for the most efficient path through states. However, this approach fails when the number of states is large due to the time to compute all possible sequences.
View Article and Find Full Text PDFAggregation of misfolded α-synuclein (aSyn) within the brain is the pathologic hallmark of Lewy body diseases (LBD), including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Evidence exists for aSyn "strains" - conformations with distinct biological properties. However, biomarkers for PD vs.
View Article and Find Full Text PDFArticle Synopsis
- The COVID-19 pandemic negatively impacted cardiovascular disease management in England, particularly affecting blood pressure screening and hypertension management.
- A study analyzed data from 25.2 million NHS patients, showing a decline in blood pressure screening from 90% in March 2019 to 85% in March 2023, while hypertension prevalence remained stable at about 15%.
- Treatment percentages for hypertension also dropped significantly during the pandemic, with patients aged ≤79 years treated to target falling from 71% to 47% and those aged ≥80 years from 85% to 58% before showing signs of recovery.