Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study.

We describe the use of gabapentin for the treatment of itching in wound healing in 35 children. All children were already treated with chlorpheniramine and trimeprazine but they remained irritable and were constantly rubbing their wounds. Within 24h of commencing treatment itching had improved significantly in all of the children.

Comparison of diclofenac and tenoxicam for postoperative analgesia with and without fentanyl in children undergoing adenotonsillectomy or tonsillectomy.

127 children scheduled for elective tonsillectomy or adenotonsillectomy were studied. Anaesthesia was induced with propofol and maintained with a volatile agent. At induction the child received either rectal diclofenac 1 mg.

Effects of analysis method and forcing waveform on measurement of respiratory mechanics.

The respiratory system has been shown to exhibit nonlinear mechanical properties in the frequency (f) range of normal breathing, manifested by tidal volume (Vt) dependence. Calculations of respiratory system resistance (R) and elastance (E) from pressure-flow measurements during external forcing at a given f may be ambiguous, especially if non-sinusoidal forcing waveforms are used. We evaluated the degree to which R and E depended upon: (1) analysis method (Fourier transform, multiple regression and pressure-volume loop analysis) and; (2) shape of the forcing waveform (sinusoidal, quasi-sinusoidal and step).

Lung, chest wall, and total respiratory system resistances and elastances in the normal range of breathing.

We measured total respiratory system and lung and chest wall resistances (Rrs, Rl, and Rcw) and elastances (Ers, El, and Ecw) in awake, relaxed human subjects during sinusoidal volume forcing at the mouth from 0.2 to 0.6 Hz with tidal volumes (VT) of 6 to 18% VC at constant mean airway pressure.

Efficacy of tracheal insufflation of oxygen during oleic acid-induced pulmonary edema.

Study Objectives: To determine whether tracheal insufflation of oxygen (TRIO) might be useful in field resuscitation of casualties with lung dysfunction.

Design: Physiological measurements of cardiac and respiratory function were compared before and after oleic acid lung injury.

Setting And Participants: Beagles were studied in a laboratory.