Discretized representations in V1 predict suboptimal orientation discrimination.

Neuronal population activity in sensory cortices is the substrate for perceptual decisions. Yet, we still do not understand how neuronal information content in sensory cortices relates to behavioral reports. To reconcile neurometric and psychometric performance, we recorded the activity of V1 neurons in mice performing a Go/NoGo orientation discrimination task.

Alcohol-based antisepsis without the use of chlorhexidine for arthroscopy in horses.

Alcohol-based antisepsis has shown experimentally to be as effective as 4 % chlorhexidine gluconate (CHG) at reducing bacterial counts (colony forming units; CFU) on equine skin. Our objectives were to determine the immediate and post-surgical reduction in CFU/mL on equine skin prepared with CHG-based or 70 % isopropyl alcohol (IPA)-based (without CHG) protocols in a clinical setting with arthroscopic surgery. Our hypotheses were that the logCFU/mL reduction would not significantly differ between protocols immediately after preparation or at the end of surgery.

Arterial effects of anthracycline: structural & inflammatory assessments in non-human primates and lymphoma patients.

Anthracyclines, such as doxorubicin, are important anti-cancer therapies but are associated with arterial injury. Histopathological insights have been limited to small animal models and the role of inflammation in the arterial toxic effects of anthracycline is unclear in humans. Our aims were: 1) To evaluate aortic media fibrosis and injury in non-human primates treated with anthracyclines; 2) To assess the effect of anthracycline on aortic inflammation in patients treated for lymphoma.

Corrigendum: Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.

[This corrects the article DOI: 10.3389/fmicb.2024.

Understanding Goal Setting and Behavior Change Mechanics in an Older Adult Sitting Reduction Intervention.

Purpose: We explored intervention fidelity, participant satisfaction, and the goals and reminder strategies participants chose to reduce sitting.

Approach: Mixed methods approach leveraging data collected during study coaching and fidelity monitoring.

Setting: A successful 6-month randomized controlled trial of a sedentary behavior (SB) intervention for adults ≥60 years in Washington, USA.