Publications by authors named "J E Malkin"
Biological synaptic transmission is unreliable, and this unreliability likely degrades neural circuit performance. While there are biophysical mechanisms that can increase reliability, for instance by increasing vesicle release probability, these mechanisms cost energy. We examined four such mechanisms along with the associated scaling of the energetic costs.
View Article and Find Full Text PDFBackground: Human papillomavirus (HPV) infection causes nearly all cervical cancer cases and is a cause of anogenital and oropharyngeal cancers. The incidence of HPV-associated cancers is inequitable, with an increased burden on marginalized groups in high-income countries. Understanding how immunization status varies by material and social deprivation, health system, and geospatial factors is valuable for prioritizing and planning HPV immunization interventions.
View Article and Find Full Text PDFBackground: As Saudi Arabia is expected to face population aging in the future, the burden of diseases arising from inadequate physical activity (PA) and excess sedentary behavior (SB) may subsequently increase without successful interventions. The present study critically reviews the global literature on the effectiveness of PA interventions targeting community-dwelling older adults to draw on lessons and applications for future interventions in Saudi Arabia.
Methods: This umbrella review of systematic reviews included interventions designed to increase PA and/or reduce SB in community-dwelling older adults.
Background: Physical inactivity among the general population is of great concern in public health.
Objective: This narrative review aims to identify promising physical activity (PA) public policies based on the best available evidence from the literature.
Methods: The study is a narrative synthesis of 'reviews of reviews' of public policies designed to increase physical activity among either (a) youths or (b) the community at large.
Article Synopsis
- Over 1,300 Canadians are diagnosed with cervical cancer each year, which could be largely prevented through HPV immunization, but current vaccination rates fall below the desired 90%.
- The Urban Public Health Network is collaborating with Alberta Health Services to investigate perceived barriers and enablers affecting youth HPV immunization as part of a school-based program in Alberta.
- The study will utilize surveys and interviews with parents and stakeholders, employing both quantitative and qualitative analyses to better understand and enhance vaccine uptake among hesitant populations.