Association of Hypertension with All-Cause Mortality among Hospitalized Patients with COVID-19.

It is unclear to which extent the higher mortality associated with hypertension in the coronavirus disease (COVID-19) is due to its increased prevalence among older patients or to specific mechanisms. Cross-sectional, observational, retrospective multicenter study, analyzing 12226 patients who required hospital admission in 150 Spanish centers included in the nationwide SEMI-COVID-19 Network. We compared the clinical characteristics of survivors versus non-survivors.

Textural analysis in the diagnosis of benign and malignant breast cells.

Objective: To study the discriminatory capacity of textural variables to classify the nuclei of breast tumor cells as benign or malignant, using a statistical approach.

Study Design: Image analysis techniques were used to automatically segment nuclei of cells obtained by fine needle aspiration and Papanicolaou stained. The sample comprised 95 cases of malignant lesions and 47 cases of benign lesions (approximately 25 nuclei per case), and 27 textural variables were measured.

Intermittent alveolar overdistension for 30 or 240 minutes does not produce acute lung injury in normal pig lung.

Background: The objective is to study whether alveolar overdistension can induce acute lung injury in pigs as assessed by analysis of respiratory and histological parameters and inflammatory markers.

Materials And Methods: Experimental study, using mixed-breed pigs. Animals were assigned to one of the following groups: Control Group (CG) (n = 5), applying mechanical ventilation with tidal volume (Vt) of 10 ml/kg, respiratory rate (RR) of 18 bpm, and FiO2 of 1 for 240 min; High Vt for 30 min (HVt-30) Group (n = 5), applying ventilation with Vt of 50 ml/kg and RR of 8 bpm and FiO2 of 1 for 30 min, followed by ventilation as in the CG for a further 210 min; and HVt-240 Group (n = 5), applying ventilation with Vt of 50 ml/kg, RR of 8 bpm, and FiO2 of 1 for 240 min.

Diagnosis of breast cancer by measuring nuclear disorder using planar graphs.

Objective: To achieve a classifier of breast lesions to distinguish benign from malignant mammary lesions by quantifying nuclear disorder in epithelial cell groups from smears obtained by fine needle aspiration.

Study Design: The study included 95 cases of breast cancer (289 groups) and 47 of benign breast lesions (150 groups), diagnosed by cytology. Information from planar graphs (mean of nuclear distances, standard deviation, maximum and minimum distance between nuclei) was used, and an algorithm constructed for this purpose was applied.

[Loss of integrity of bipolar cardiac stimulation and its automatic correction. Report of 2 cases].

We report two patients with DDD and VVI pacemakers respectively, in whom telemetry revealed a markedly high bipolar ventricular lead impedance, suggestive of a fracture or other defect in bipolar lead. Pulse generator was able to switch automatically to unipolar pacing, and a loss of ventricular capture was prevented.