Publications by authors named "J E Justman"

Background: Vaccine hesitancy has been a significant concern throughout the COVID-19 pandemic. Vaccine hesitancy can be attributed to lack of confidence in vaccines, complacency about the health threat, or lack of convenience of vaccination. To date, few studies have used methods designed to include populations underrepresented in research when identifying factors associated with vaccine hesitancy.

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Article Synopsis
  • HIV and syphilis are commonly found in sub-Saharan Africa, and a study aimed to look at active syphilis prevalence while factoring in HIV status and demographic details across five countries: Ethiopia, Tanzania, Uganda, Zambia, and Zimbabwe.
  • The study involved over 100,000 participants aged 15 and older, who provided demographic and behavioral data along with blood samples for testing. Active syphilis was identified using specific antibody tests, and results were analyzed using statistical models.
  • Results showed varying syphilis prevalence rates across the countries, with an estimated 1,027,615 individuals affected; those living with HIV had notably higher syphilis rates compared to those without HIV.
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  • The study investigates the prevalence of monoclonal gammopathy of undetermined significance (MGUS) in Eswatini, comparing it with data from Olmsted County, Minnesota, to understand its impact, particularly among Black individuals.
  • A total of 515 plasma samples from a nationally representative survey showed a 13.2% prevalence of MGUS, with findings indicating that while overall MGUS rates are similar between Eswatini and Olmsted County, light-chain MGUS is significantly higher in Eswatini.
  • The results suggest that current definitions of light-chain MGUS may need reevaluation, particularly in the context of untreated HIV infections, as they could be reflecting different underlying conditions.
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Background: Lack of point-of-care testing (POCT) for sexually transmitted infections (STIs) is a continuing missed opportunity in Sub-Saharan Africa. We assessed feasibility and acceptability of STI POCT in Eswatini.

Methods: Sexually transmitted infection POCT for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) was piloted among sexually active adults 18 to 45 years old attending 2 urban outpatient clinics offering integrated services.

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