Publications by authors named "J E Johansson"

Article Synopsis
  • Recent studies showed only weak connections between age, dopamine receptor availability, and cognitive decline, suggesting more research is needed.
  • Longitudinal data over five years found that older adults who experienced declines in D2/3 dopamine receptors had worse working memory performance over time.
  • Specifically, the decline in dopamine receptor availability was significant in key brain regions linked to working memory, supporting the idea that dopamine changes contribute to cognitive aging.
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Objective: To investigate if eye tracking can support detection of covert voluntary eye movements and to compare these findings with a simultaneously performed clinical assessment according to the Coma Recovery Scale manual regarding visual stimuli.

Design: Observational case series.

Subjects: Twelve outpatients with prolonged disorders of consciousness recruited from the rehabilitation clinic of a regional rehabilitation unit.

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The 1991 film The Silence of the Lambs tracks the fictional pursuit of an American serial killer by a Federal Bureau of Investigation trainee, via the assistance of another incarcerated serial killer. It features psychologically disturbing themes, such as corpses, the mutilation of skin and monstrous persons. Incidentally, these are all themes regularly encountered by nurses in their day-to-day practices, including forensic mental health nurses.

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: Flow cytometry is a convenient tool in immunophenotyping for monitoring the status of immunological conditions and diseases. The aim of this study was to investigate the effect of isolation and cryopreservation by flow cytometric analysis on subpopulations of CD4 T helper (Th), T regulatory (Treg), CD8 T cytotoxic (Tc), CD56 NK, CD19 B and monocytes. Freshly isolated and cryopreserved peripheral blood mononuclear cells (PBMCs) were compared to fresh whole blood.

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Treatment strategies that are efficient against established Alzheimer's disease (AD) are needed. BRICHOS is a molecular chaperone domain that prevents amyloid fibril formation and associated cellular toxicity. In this study, we treated an AD mouse model seven months after pathology onset, using intravenous administration of recombinant human (rh) Bri2 BRICHOS R221E.

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