A 2D detector array for relative dosimetry and beam steering for FLASH radiotherapy with electrons.

Background: FLASH radiotherapy is an emerging treatment modality using ultra-high dose rate beams. Much effort has been made to develop suitable dosimeters for reference dosimetry, yet the spatial beam characteristics must also be characterized to enable computerized treatment planning, as well as quality control and service of a treatment delivery device. In conventional radiation therapy, this is commonly achieved by beam profile scans in a water phantom using a point detector.

Strategic uniqueness seeking: A cultural perspective.

Building on the perspectives reflected in the Western intellectual tradition of the psychology of identity and the self, current research in cultural psychology tends to conceptualize uniqueness preferences as reflecting an identity-based motive and argues that people in Western cultures value uniqueness because it is viewed as inherently important to their identity and individuality. In this research, we introduce a complementary Eastern perspective to understand uniqueness preferences and argue that uniqueness preferences can also reflect a strategic motive where people in East Asian cultures may also value uniqueness because of the instrumental material and social benefits they believe uniqueness may confer. We tested our propositions in nine preregistered studies contrasting the decision making of people in the United States with those in China.

Partnering up (and down): Examining when and why people prefer collaborating with higher paid peers (and lower paid subordinates).

Emerging trends toward greater pay transparency and more freedom in teaming decisions intersect to highlight a potential conflict. Extant research suggests that visible pay disparities should adversely affect collaborations, particularly with higher paid partners, but we challenge this thesis and present three preregistered studies demonstrating that visible salary disparities can positively affect collaboration with higher paid peers in teaming decisions. In Studies 1 and 2, people chose to collaborate with higher rather than lower paid peers unless explicitly told that their potential collaborators' knowledge, skills, abilities, and experience were similar, suggesting that pay was viewed as a signal for competence.

Status and subjective well-being: A conceptual replication and extension of Anderson et al. (2012).

Does the status people possess shape their subjective well-being (SWB)? Prior research that has addressed this question has been correlational. Therefore, in the current research, we provide causal evidence of this effect: In two experiments, we found that individuals reported higher SWB when their own status was higher compared to when it was lower. However, individuals' SWB was not only shaped by their own status, but also by others' status.

Anti-DEFA5 Monoclonal Antibody Clones 1A8 and 4F5 Immunoreactive Bioassay for Diagnosing Inflammatory Bowel Disease.

Background: Robust evidence suggests that the aberrant expression of α defensin 5 protein (DEFA5) in colon inflammatory bowel diseases (IBDs) underlies the distinct pathogenesis of Crohn's colitis, can be exploited as a reliable diagnostic biomarker to differential diagnosis of Crohn's colitis (CC) from Ulcerative colitis (UC) in otherwise indeterminate colitis (IC). We evaluated the specificity of the commercially available anti-DEFA5 antibodies and showed further validation of their appropriateness for a given application is required.

Methods: We established two mouse monoclonal DEFA5 antibody clones 1A8 and 4F5 by immunizing the mice with purified recombinant protein and validated the specificity, selectivity and cross reactivity in recognizing the endogenous and recombinant DEFA5 protein, especially for Immunohistochemistry, Western blot, Immunoprecipitation, or enzyme-linked immunosorbent assay.