Publications by authors named "J E Heathcote"
Article Synopsis
- This study compared the measurement of geographic atrophy (GA) in the macula using two imaging methods: standard 30° field fundus autofluorescence (FAF) and ultrawide field (UWF) FAF.
- Participants from specific eye disease studies were analyzed over a period of 5 years, focusing on the GA area measured by both imaging techniques.
- The results showed that GA measurements were typically larger with standard FAF than UWF FAF, but both methods demonstrated similar rates of progression, indicating that UWF FAF can be a valid option for long-term monitoring of GA.
Article Synopsis
- The study focuses on tubulointerstitial fibrosis as a key feature of chronic kidney disease (CKD) in cats, exploring how varying durations of ischemia influence kidney damage models in domesticated cats.
- Young adult cats underwent 90 minutes of induced ischemia in one kidney, followed by nephrectomy at different time intervals to assess renal functionality and histological changes.
- Results showed that both ischemic groups experienced significant declines in kidney function, higher injury scores, and increased fibrosis compared to the control group, indicating severe impairment after renal ischemia.
Purpose: The curation of images using human resources is time intensive but an essential step for developing artificial intelligence (AI) algorithms. Our goal was to develop and implement an AI algorithm for image curation in a high-volume setting. We also explored AI tools that will assist in deploying a tiered approach, in which the AI model labels images and flags potential mislabels for human review.
View Article and Find Full Text PDFIn this paper we ask how to best allocate a given time-varying supply of vaccines during the second phase of the Covid-19 pandemic across individuals of different ages. Building on our previous heterogeneous household model of optimal economic mitigation and redistribution (Glover et al., 2021) we contrast the actual vaccine deployment path that prioritized older, retired individuals with one that first vaccinates younger workers.
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