Suppression of a Transketolase Mutation Leads to Only Partial Restoration of Symbiosis in .

The interaction between and alfalfa is a well-studied model system for symbiotic establishment between rhizobia and legume plants. Proper utilization of carbon sources has been linked with effective symbiotic establishment in strain Rm1021. Previous work has shown that mutation of the gene , which encodes a transketolase involved in the pentose phosphate pathway, resulted in a strain impaired in many biological functions, including the inability to establish a symbiosis with alfalfa.

Trajectories of mental health across the primary to secondary school transition.

Background: Adolescence is a period of profound developmental change during which the prevalence of mental health problems starts to increase. It also typically coincides with a school transition. Understanding mental health trajectories through school transition is important to inform interventions to support young people's mental health during this period.

Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine.

Adhesion of E. coli to the urinary tract epithelium is a critical step in establishing urinary tract infections. FimH is an adhesin positioned on the fimbrial tip which binds to mannosylated proteins on the urinary tract epithelium via its lectin domain (FimHLD).

Derived datasets of daily weather, near surface soil status, flow rates and concentrations of nitrogen species from the North Wyke farm platform, England.

Weather conditions, hydrological responses and the dynamics of key nitrogen species in field runoff were continuously monitored at 15-min resolution on the intensively instrumented North Wyke Farm Platform (NWFP), a UK National Bioscience Research Infrastructure (NBRI), to support research on sustainable and resilient agriculture in the UK. Released data spanning 2013 to 2024 for 6 selected field catchments were aggregated to daily timestep, with reference to data quality flags, to produce continuous weather data, including maximum and minimum air temperature, daily total rainfall, wind speed and quality assured daily average soil moisture content, soil temperature at 15 cm depth, runoff rates, as well as nitrate, nitrite and ammonium concentrations. External data sources were sourced to infill some gaps for the weather data and summary statistics on data coverage were generated for the other data on an annual and seasonal basis where appropriate.