Two sides of the same coin: Weathering differences of plastic fragments in coastal environments around the globe.

Plastic debris in coastal environments usually undergoes weathering due to various environmental conditions. However, the weathering effects on exposed and shaded sides of the same plastics are underexplored. In this study, 1573 plastic fragments were collected from 15 coastal sites worldwide between December 2021 and December 2022, and weathering experiments were conducted outdoors.

Antioxidant properties of phenolic extracts of murtilla pomace: First report on the importance of soluble and insoluble-bound compounds.

Some native Chilean berries, including murtilla, have gained attention for their high phenolic content which renders them attractive for the beverage industry. However, phenolic-rich by-products are generated during the production of murtilla juice (murtilla pomace), and there has been no scientific consideration of this by-product as a source of different forms of phenolic compounds. The aim of this study was thus to obtain phenolic extracts from the soluble fraction (free, esterified, and etherified) of murtilla pomace as well from the counterpart that contains insoluble-bound compounds, and evaluate their antioxidant properties.

Anticholinesterase and Anti-Inflammatory Activities of the Essential Oils of Sawdust and Resin-Rich Bark from Azorean (Cupressaceae): In Vitro and In Silico Studies.

Alzheimer's disease (AD), a multifactorial neurodegenerative disorder characterized by severe cognitive impairment, affects millions of people worldwide. However, AD therapy remains limited and mainly symptomatic-focused, with acetylcholinesterase (AChE) inhibitors being the major available drugs. Thus, AD is considered by the WHO as a disorder of public health priority.

An Effective Liposome-Based Nanodelivery System for Naphthalene Derivative Polyamines with Antitumor Activity.

This study focuses on the development of a novel liposome-based nanodelivery system designed to encapsulate polyamine-1, a compound with potential anti-tumor properties. The main objective of this work was to enhance the therapeutic and imaging potential of polyamine-1 by incorporating it into liposome-based nanoparticles, which were functionalized with a gadolinium complex for imaging purposes and a fluorescent phospholipid for tracking applications. These nanoparticles were characterized by measuring their size, shape, polydispersity index, zeta potential and encapsulation efficiency.

Revealing the Bioactivities of Venom Using as a Model.

, commonly known as the Portuguese Man o' War, is one of the most venomous members of the Cnidaria yet is poorly understood. This article investigates the toxicity of venom by assessing its behavioral and toxicological effects on . The venom administered orally revealed dose- and time-dependent mortality, with an LD50 of 67.