Publications by authors named "J E Edlund"
Replications are important for assessing the reliability of published findings. However, they are costly, and it is infeasible to replicate everything. Accurate, fast, lower-cost alternatives such as eliciting predictions could accelerate assessment for rapid policy implementation in a crisis and help guide a more efficient allocation of scarce replication resources.
View Article and Find Full Text PDFChemical exposomics in biobanked plasma samples and associations with breast cancer risk factors.
J Expo Sci Environ Epidemiol
December 2024
Background: The chemical exposome includes exposure to numerous environmental and endogenous molecules, many of which have been linked to reproductive outcomes due to their endocrine-disrupting properties. As several breast cancer risk factors, including age and parity, are related to reproduction, it is imperative to investigate the interplay between such factors and the chemical exposome prior to conducting large scale exposome-based breast cancer studies.
Objective: This pilot study aimed to provide an overview of the chemical exposome in plasma samples from healthy women and identify associations between environmental exposures and three risk factors for breast cancer: age, parity, and age at menarche.
Article Synopsis
- Hydraulic force, a new mechanism that supports diastolic filling in the heart, is measured through the difference in short-axis areas between the left ventricle and atrium during heart cycles.
- The study aimed to see how this area difference (AVAD) changes from rest to exercise in both sedentary individuals and athletes by using cardiovascular magnetic resonance imaging (CMR).
- Findings showed that AVAD increased during moderate exercise, enhancing diastolic filling, but did not show further increase during vigorous exercise; athletes maintained stable AVAD while sedentary controls saw a decrease with higher intensity activities.