Publications by authors named "J E Dominguez"
Pediatric femur fractures often necessitate surgical intervention, with pain management being critical for both immediate and long-term outcomes. Peripheral nerve blocks (PNBs) and neuraxial techniques are effective in providing targeted pain relief while minimizing systemic opioid exposure. Despite their benefits, the utilization of these anesthesia techniques in pediatric orthopedic surgeries is limited, particularly among socioeconomically disadvantaged patients.
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- The study investigated the link between untreated obstructive sleep apnea and the severity of postoperative neurocognitive disorders in older patients undergoing noncardiac surgery.
- Despite 58 of 96 subjects testing positive for sleep apnea, the analysis showed that the severity of sleep apnea did not correlate with increased cognitive decline or the incidence of neurocognitive disorders at 6 weeks or 1 year after surgery.
- Results remained consistent even after adjusting for factors like age, sex, and baseline cognition, indicating that sleep apnea severity may not be a significant risk factor for cognitive issues post-surgery.
The pediatric population is one of the social groups most affected by oral pathology, and overweight and/or obesity is increasingly frequently observed. This work presents a study of the prevalence of oral disease in the school population in Mallorca and its relationship with overweight/obesity. A cross-sectional study was carried out with a sample of 718 students aged 5-6 ( = 255), 12 ( = 230) and 15 years ( = 233).
View Article and Find Full Text PDFBackground And Objective: Due to the potential debilitating sequelae following pediatric mTBI, the CDC published the Guideline on the Diagnosis and Management of mTBI Among Children in 2018. However, the guideline identified several key gaps in our clinical knowledge to support several clinical recommendations. The objective of this review is to evaluate if subsequent research has addressed these gaps in clinical practice recommendations.
View Article and Find Full Text PDFAutoantibodies contribute to many autoimmune diseases, yet there is no approved therapy to neutralize them selectively. A popular mouse model, experimental autoimmune encephalomyelitis (EAE), could serve to develop such a therapy, provided we can better understand the nature and importance of the autoantibodies involved. Here we report the discovery of autoantibody-secreting extrafollicular plasmablasts in EAE induced with specific myelin oligodendrocyte glycoprotein (MOG) antigens.
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