A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease.

Alveolar type 2 (AT2) cells maintain lung health by acting as stem cells and producing pulmonary surfactant. AT2 dysfunction underlies many lung diseases, including interstitial lung disease (ILD), in which some inherited forms result from the mislocalization of surfactant protein C (SFTPC) variants. Lung disease modeling and dissection of the underlying mechanisms remain challenging due to complexities in deriving and maintaining human AT2 cells ex vivo.

Open Latarjet Results in Lower Recurrent Instability and Revision Rates Than Arthroscopic Bankart Repair at 10-Year Follow-up: A Systematic Review.

Purpose: To compare arthroscopic Bankart repair versus the open Latarjet procedure at a minimum of 10-year follow-up evaluating recurrence and arthropathy development rates.

Methods: A systematic review was performed in concordance with PRISMA guidelines. Studies were included if they reported on the arthroscopic Bankart repair or open Latarjet procedure with a minimum of 10-year follow-up.

Editorial Commentary: Failure to Return to Sport Following Latarjet May Be Due to Diverse Causes: Psychological Reasons Are Most Common.

The Latarjet procedure is a successful treatment for anterior shoulder instability with less than 5% having redislocations - revision surgery and prior surgery having been shown to be significant risk factors for recurrence. Approximately 90% of athletes return to play after Latarjet, comparable to arthroscopic Bankart repair. Patients may be physically unable to return to play, which may be due to persistent pain, apprehension, or weakness.

Return to Play After Arthroscopic Superior Labral Repair: A Systematic Review.

Background: Superior labral tears are common shoulder injuries among athletes, and for athletes undergoing surgical intervention, one of the main priorities is to return to preinjury levels of activity in a timely manner. However, the literature surrounding return to play after superior labral repair presents inconsistent results, with limited studies evaluating the timing of return to play.

Purpose: To systematically review the rate and timing of return to play in athletes after arthroscopic superior labral repair.

Mid- to Long-Term Clinical Outcomes and Failure Rates After ALPSA Lesion Repair.

Background: Anterior labroligamentous periosteal sleeve avulsion (ALPSA) lesions are associated with recurrent shoulder instability and higher rates of failure after capsulolabral repair compared with similarly treated Bankart lesions. Although these lesions can portend poor outcomes, there are limited data on the associated conditions and postoperative course in a young, active population.

Purpose: To evaluate the mid- to long-term clinical course and failure rates after ALPSA repairs and assess features associated with these outcomes.