Publications by authors named "J E Demers"

Objective: This systematic review assessed the socioeconomic and demographic factors influencing interpersonal communication between family physicians and patients with chronic diseases.

Methods: We searched three databases (Embase, MEDLINE, and Cochrane) for published empirical studies reporting interpersonal communication between adults with chronic conditions and their family physicians. Gender, sex, race or ethnicity, low levels of literacy and/or health knowledge, and lower level of education or income were the factors of interest.

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Article Synopsis
  • Cardiovascular diseases (CVDs) are serious health problems that affect both men and women, but there are some differences in how they impact each gender.
  • The study looked at how work stress and conditions relate to CVDs in men and women, finding that many studies don’t fully separate results for each gender.
  • Although researchers are starting to pay more attention to gender differences, there are still big gaps in research that need to be filled to help improve heart disease prevention for everyone.
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NMDA receptor antagonists have potential for therapeutics in neurological and psychiatric diseases, including neurodegenerative diseases, epilepsy, traumatic brain injury, substance abuse disorder (SUD), and major depressive disorder (MDD). ()-ketamine was the first of a novel class of antidepressants, rapid-acting antidepressants, to be approved for medical use. The stereoisomer, ()-ketamine (arketamine), is currently under development for treatment-resistant depression (TRD).

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Spinal cord injury (SCI) afflicts millions of individuals globally. There are few therapies available to patients. Ascending and descending excitatory glutamatergic neural circuits in the central nervous system are disrupted by SCI, making α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) a potential therapeutic drug target.

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Background: Interest in the financial burden of informal caregivers has been growing. Unfortunately, it remains unclear which method(s) should be used when quantifying this burden.

Purpose: We conducted a scoping review aimed at identifying which methods have been used to conduct such work and quantified their performance.

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