Publications by authors named "J E Costa Bianchi"
Objective: This retrospective study aimed to evaluate morphometric changes in mandibular condyles of patients with skeletal Class III malocclusion following two-jaw orthognathic surgery planned using virtual surgical planning (VSP) and analysed with automated three-dimensional (3D) image analysis based on deep-learning techniques.
Materials And Methods: Pre-operative (T1) and 12-18 months post-operative (T2) Cone-Beam Computed Tomography (CBCT) scans of 17 patients (mean age: 24.8 ± 3.
Background: Hamstring injuries can have a significant burden on a professional football player's career and performance. One in 4 players will suffer a lower extremity strain in their career, with the hamstring being the most common. These injuries are often fraught with extended periods of recovery and reinjury rates varying between 16% and 38%.
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- Investigating chromosomal instability and aneuploidy is crucial for understanding how tumors develop and creating better diagnostic and treatment methods.
- The new method, KaryoTap, combines targeted DNA sequencing with advanced computational tools to efficiently detect chromosomal gains, losses, and neutral variants across thousands of single cells.
- KaryoTap shows high accuracy in identifying chromosomal changes and has the potential to enhance research on aneuploidy in both tumor and normal cells, enabling functional screening with CRISPR technology.
Objective: This study evaluated the force system generated by the Memory Titanol® spring (MTS) with different preactivation bends using an orthodontic force tester (OFT).
Methods: Three preactivations were tested using a 0.017 × 0.
Background: The epigenome, the set of modifications to DNA and associated molecules that control gene expression, cellular identity, and function, plays a major role in mediating cellular responses to outside factors. Thus, evaluation of the epigenetic state can provide insights into cellular adaptions occurring over the course of disease.
Methods: We performed epigenome-wide association studies of primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) using the Illumina MethylationEPIC Bead Chip.