Publications by authors named "J E Brinn"

Eastern North Carolina, roughly the northern half of the region east of Interstate 95, is a largely rural region that is in transition from a family farm-related economy to small manufacturing and retirement communities. Poor education and the typical poverty-related diseases are endemic. It is served by one academic medical center, the Brody School of Medicine at East Carolina University, and a network of hospitals affiliated with the primary referral site, a 740-bed facility in Greenville.

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Objective: To identify variables that may enhance medical student's preparedness for computer-based administration of the United States Medical Licensing Examination (USMLE).

Design: A cross-sectional survey of 301 medical students who completed a self-administered questionnaire.

Measurements: The questionnaire was designed to obtain information about students' computer resources, personal experience with computers, computer expertise, opinions about computers, experience with computer-based testing, perceived preparedness for the computer-based USMLE, and demographic variables.

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In addition to the catecholamines (CAs) dopamine (DA), norepinephrine (NE) and epinephrine (E), perifused chromaffin cells of the eel secrete codeine and morphine. In controls, the release of NE and E is strongly correlated, while there is no correlation with DA. Low, physiological concentrations of codeine (500 pg/ml) reduce the release of NE and E, while 8-fold higher concentrations stimulate an instant, transitory release of all three CAs.

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The insulin response of 3-day old neonatal rat islets was evaluated following a 1 h incubation with glucose alone and in the presence of 30 nM sulfated cholecystokinin octapeptide (CCK) and/or 20 microM carbachol (CCh). Insulin secretion was found to be incrementally increased from the lowest glucose concentration and enhanced several fold in the presence of CCK and/or CCh. In combination, CCK and CCh increased glucose-stimulated insulin secretion by an amount equivalent to the sum of their individual increases.

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