Publications by authors named "J Dworkin"

Article Synopsis
  • Research on parent-adolescent communication through technology has been limited, despite rapid changes in communication tools.
  • This study involved 404 parent-adolescent pairs and identified four distinct patterns of communication based on frequency and preferred methods (in-person, phone calls, texts, video calls).
  • Findings indicate demographic differences in communication styles and show that these communication profiles are linked to varying levels of perceived closeness between parents and adolescents.
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Background: Memory decline is common in multiple sclerosis (MS), although pathophysiological mechanisms are not fully understood.

Objective: The objective was to investigate the relationship of changes in structural and functional neuroimaging markers to memory decline over 3-year follow-up.

Methods: Participants with MS underwent cognitive evaluation and structural, diffusion, and functional 3T magnetic resonance imaging (MRI) scans at baseline and 3-year follow-up.

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Article Synopsis
  • * The research simulated the aqueous alteration processes of residues from irradiated interstellar ice, using minerals like serpentinite and the Allende meteorite to study amino acid changes.
  • * Results showed that minerals and their types crucially affect the creation and breakdown of amino acids during these simulated experiments.
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Understanding how organics degrade under galactic cosmic rays (GCRs) is critical as we search for traces of ancient life on Mars. Even if the planet harbored life early in its history, its surface rocks have been exposed to ionizing radiation for about four billion years, potentially destroying the vast majority of biosignatures. In this study, we investigated for the first time the impact of simulated GCRs (using gamma rays) on several types of lipid biosignatures (including hopane C, sterane C, alkanes, and fatty acids [FAs]) in both the presence and absence of salts (NaCl, KCl, and MgCl).

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Article Synopsis
  • Modern life is homochiral, meaning it primarily utilizes D-sugars in nucleic acids and L-amino acids in proteins, suggesting a significant evolutionary process.
  • The concept of a prebiotic RNA World implies that L-amino acids arose due to chiral transfer from an earlier D-RNA World, facilitated by aminoacyl-RNAs that helped develop the genetic code.
  • Research using D-ribozymes shows that while there is detectable chiral selectivity favoring certain enantiomers, it does not support the idea that D-RNA inherently prefers to react with L-amino acids, indicating that L-proteins can originate from different chiral contexts.
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