Publications by authors named "J Durrieu"

The profile of nursing home (NH) residents has changed over the past decade with more dependency, more severe chronic diseases and more treatments prescribed. For residents, the major consequence is the higher risk of unplanned hospitalization. French guidelines recommend the development of interactive telemedicine () in NHs in order to improve access to care, and to decrease the rate of avoidable unplanned hospitalizations.

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Decreased health-related quality of life (HRQoL) is common in patients with cancer. We investigated the effects of dietary intervention and baseline nutritional status on worsening of HRQoL in older patients during chemotherapy. In this randomized control trial assessing the effect on mortality of dietary advice to increase dietary intake during chemotherapy, this post hoc analysis included 155 patients with cancer at risk of malnutrition.

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Article Synopsis
  • This study explored how a healthy diet intervention can influence inflammation, depressive symptoms, and health-related quality of life (HRQoL) among older adults.
  • It involved 125 participants aged 65-80 from Italy, France, and Germany, divided into four groups, each receiving a different combination of healthy diets and supplements.
  • Results showed significant reductions in depressive symptoms across all groups, especially among those with higher inflammation levels, although changes in anxiety and physical components of HRQoL were minimal.
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Background: Antibiotic administration by subcutaneous (SC) injection is common practice in French geriatric wards as an alternative to the intravenous (IV) route, but few pharmacokinetic/pharmacodynamic data are available. Ertapenem is useful for the treatment of infections with ESBL-producing enterobacteria.

Objectives: To report and compare ertapenem pharmacokinetic data between IV and SC routes in older persons.

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Background: Older adults with cancer experience negative long-term functional effects of both cancer and treatments. Exercise may minimize their age-related and cancer-related functional decline.

Methods: We conducted a multicentre open-label 12 month randomized clinical trial with two parallel arms including participants aged ≥70 years with lymphoma or carcinoma requiring curative treatment.

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