Long-term efficacy and safety of antitumour necrosis factor alpha treatment in rhupus: an open-label study of 15 patients.

Background: The efficacy of antitumour necrosis factor alpha (anti-TNF-α) treatment is well recognised in rheumatoid arthritis (RA) but remains controversial in systemic lupus erythematosus (SLE). Therefore, the role of anti-TNF-α treatment in 'Rhupus', a disease sharing features of RA and SLE, is still debated.

Objective: To evaluate the efficacy and tolerance of anti-TNF-α in patients with rhupus.

Pitfalls in osteoarticular imaging: how to distinguish bone infection from tumour?

In this article examining pitfalls in osteoarticular imaging we examine the differential diagnosis of osteomyelitis from bone tumours. We describe the different features which differentiate these two types of disease in radiology and CT and MRI scanning.

Intercostal myositis ossificans misdiagnosed as osteosarcoma in a 10-year-old child.

Myositis ossificans (MO) is a rare benign cause of heterotopic bone formation within soft tissue. It most commonly affects adolescents and young adults, typically in the limbs and following trauma. Very few cases have been reported in children.