Publications by authors named "J Dunst"
Purpose: The aim of this review is to give an overview of the results of prospective and retrospective studies using allogenic reconstruction and postmastectomy radiotherapy (PMRT) in breast cancer and to make recommendations regarding this interdisciplinary approach.
Materials And Methods: A PubMed search was conducted to extract relevant articles from 2000 to 2024. The search was performed using the following terms: (breast cancer) AND (reconstruction OR implant OR expander) AND (radiotherapy OR radiation).
Article Synopsis
- - The study focuses on Stereotactic Arrhythmia Radioablation (STAR) as a treatment for ventricular tachycardia (VT), especially when traditional catheter-based methods are not viable, emphasizing the challenges in accurately defining treatment targets based on electro-anatomic maps (EAM).
- - Two different software solutions were evaluated for their effectiveness in transferring 2D target data from EAM into 3D CT volume coordinates, with a cross-validation study conducted on data from ten patients.
- - Results showed that the target volumes and surface areas obtained from both methods were nearly identical, suggesting that both software solutions are reliable for ensuring quality assurance and enhancing treatment accuracy in STAR procedures.
Upregulation of diverse self-antigens that constitute components of the inflammatory response overlaps spatially and temporally with the emergence of pathogen-derived foreign antigens. Therefore, discrimination between these inflammation-associated self-antigens and pathogen-derived molecules represents a unique challenge for the adaptive immune system. Here, we demonstrate that CD8 T cell tolerance to T cell-derived inflammation-associated self-antigens is efficiently induced in the thymus and supported by redundancy in cell types expressing these molecules.
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- The review aimed to assess the effectiveness of radiotherapy in managing brain metastases and leptomeningeal carcinomatosis in breast cancer patients and to provide treatment recommendations based on existing literature.
- A comprehensive search was conducted through PubMed for studies published between 1985 and May 2023, focusing on various types of radiotherapy for breast cancer-related brain metastases.
- Conclusions indicate that while specific radiotherapy guidelines show variability based on breast cancer subtypes, stereotactic radiosurgery is generally recommended for 1-4 brain metastases, while whole-brain radiotherapy is advised for multiple cases, especially in symptomatic patients, although treatment plans should be tailored and may include reevaluating local options after several weeks.