A Comparison of Quality and Reliability of YouTube Videos About the MRI Technique and Its Various Aspects.

Introduction: The Magnetic Resonance Imaging (MRI) machine is a subset of nuclear magnetic resonance imaging technology that produces images of the body using magnetic field gradients. The MRI Machine has two components: the computer-based control centre room and the adjacent MRI machine room where the patient undergoes the scan.

Aims: This study aimed to assess the quality and reliability of YouTube videos about MRI machines, MRI scans, and MRI claustrophobia and compare the quality and reliability of the videos among different types of uploaders.

Reactivities of acrylamide warheads toward cysteine targets: a QM/ML approach to covalent inhibitor design.

Covalent inhibition offers many advantages over non-covalent inhibition, but covalent warhead reactivity must be carefully balanced to maintain potency while avoiding unwanted side effects. While warhead reactivities are commonly measured with assays, a computational model to predict warhead reactivities could be useful for several aspects of the covalent inhibitor design process. Studies have shown correlations between covalent warhead reactivities and quantum mechanic (QM) properties that describe important aspects of the covalent reaction mechanism.

[Translated article] Immobilisation with compression bandage vs. antebraquial splint in distal radius fractures operated by open reduction and locking plate. Randomised clinical trial.

Introduction: Currently, there is a lack of prospective studies to unify criteria about type and time for postoperative immobilisation in surgical distal radius fractures. The aim of this study is to compare functional and radiological results in two groups of distal radius fractures treated with internal fixation with locking plate, and immobilised with antebrachial splint or compression bandage for 3 weeks.

Material And Method: A randomised clinical trial was carried out with two parallel groups with 3, 6, and 12 weeks of follow-up.

Martini 3 Force Field Parameters for Protein Lipidation Post-Translational Modifications.

Protein lipidations are vital co/post-translational modifications that tether lipid tails to specific protein amino acids, allowing them to anchor to biological membranes, switch their subcellular localization, and modulate association with other proteins. Such lipidations are thus crucial for multiple biological processes including signal transduction, protein trafficking, and membrane localization and are implicated in various diseases as well. Examples of lipid-anchored proteins include the Ras family of proteins that undergo farnesylation; actin and gelsolin that are myristoylated; phospholipase D that is palmitoylated; glycosylphosphatidylinositol-anchored proteins; and others.