Analysis of HLA-G 5'URR regulatory polymorphisms in Slovak women with pre-eclampsia.

Objectives: The objective of this study was to identify the impact of the selected HLA-G gene polymorphisms in the 5'URR region on the risk to develop pre-eclampsia.

Background: Pre-eclampsia (PE) is a serious multisystem disorder that affects women during pregnancy. Despite many research studies, the pathology of PE is not fully understood.

Dependence of the damage in optical metal/dielectric coatings on the energy of ions in irradiation experiments for space qualification.

Terrestrial accelerator facilities can generate ion beams which enable the testing of the resistance of materials and thin film coatings to be used in the space environment. In this work, a [Formula: see text]/Al bi-layer coating has been irradiated with a [Formula: see text] beam at three different energies. The same flux and dose have been used in order to investigate the damage dependence on the energy.

Analysis of HLA-G gene polymorphisms in Slovak women with pre-eclampsia.

Objectives: To identify possible association between the selected HLA-G gene polymorphisms and risk of pre-eclampsia.

Background: Pre-eclampsia is a serious multisystem disorder that affects women during pregnancy. Despite many research studies, the pathology of pre-eclampsia is not fully understood.

Longitudinal evaluation of markers of hemostasis in pregnancy.

Objective: The aim of this study was to establish the physiologic changes in hemostasis during pregnancy and to find the association between the factor V Leiden mutation and adverse pregnancy outcome.

Methods: We investigated blood samples of 148 pregnant women during each trimester of pregnancy. We measured their serum concentrations of factors I, II, V, VII, VIII, IX, X, XI, XII, D-dimers, prothrombin time, INR, aPTT, activity of protein C and S, antithrombin III and platelet count.

Ultrasound diagnosis of macrosomia.

Over the last two to three decades, there has been a 15-25 % increase in many countries in the number of women giving birth to large infant. Fetal macrosomia is associated with an increased risk of complications both for the mother and the newborn. In current obstetrics, the macrosomic fetus represents a frequent clinical challenge.