Publications by authors named "J Drenthen"

Background And Purpose: Various electrodiagnostic criteria have been developed in Guillain-Barré syndrome (GBS). Their performance in a broad representation of GBS patients has not been evaluated. Motor conduction data from the International GBS Outcome Study (IGOS) cohort were used to compare two widely used criterion sets and relate these to diagnostic amyotrophic lateral sclerosis criteria.

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Background: Current diagnostic methods for nerve compression headaches consist of diagnostic nerve blocks. A less-invasive method that can possibly aid in the diagnosis is ultrasound, by measuring the cross-sectional area (CSA) of the affected nerve. However, this technique has not been validated, and articles evaluating CSA measurements in the asymptomatic population are missing in the current literature.

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Background And Objectives: Chronic axonal polyneuropathy is a common disease of the peripheral nervous system with increasing prevalence with age. Typical neurologic signs are present in patients with polyneuropathy but may also occur in individuals without disease. Owing to limited knowledge on normal aging of the peripheral nervous system, it can be difficult to distinguish peripheral nerve dysfunction due to disease from variations in normal aging.

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Article Synopsis
  • Chronic axonal polyneuropathy is becoming more common with age and significantly impacts daily life, but many individuals do not seek medical help, leading to underreporting of its prevalence.
  • A study conducted from 2013 to 2020 in the Netherlands included over 4,000 participants and found that the age-standardized prevalence of the condition was about 3% in Europe and the U.S., and projected to increase by 25% in the next 20 years.
  • Many participants had undiagnosed polyneuropathy, with notable risk factors including diabetes and vitamin deficiencies, and over 20% of cases exhibited multiple risk factors.
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