Publications by authors named "J Diaz-Gomez"
Background: self-efficacy in breastfeeding influences the duration of breastfeeding. There is a validated scale to measure it, the Breastfeeding Self Efficacy Scale-Short Form (BSES-SF), developed by Dennis et al. AIMS: to examine the internal structure of the BSES-SF, verify if the score changes in the first months of lactation and if it is related to early cessation of breastfeeding.
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- The study explores how the PD-1 immune checkpoint protein is regulated on CD8 T cells, aiming to find ways to lower its abundance without hindering T cell activation, which is crucial for effective cancer therapy.
- Researchers conducted a CRISPR-Cas9 screen on murine CD8 T cells to identify genes impacting PD-1 levels, discovering that inhibiting the TMED protein family, especially TMED10, could reduce PD-1 on the cell surface and enhance T cell function.
- The findings highlight a new regulatory mechanism for PD-1 and suggest that targeting TMED could be a promising therapeutic strategy to improve T cell responses in cancer treatment, as indicated by correlations in mouse models and patient survival data.
Point-of-care ultrasound (POCUS) involves the acquisition, interpretation, and immediate clinical integration of ultrasonographic imaging performed by a treating clinician. The current state of cardiac POCUS terminology is heterogeneous and ambiguous, in part because it evolved through siloed specialty practices. In particular, the medical literature and colloquial medical conversation contain a wide variety of terms that equate to cardiac POCUS.
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