Publications by authors named "J Diaz-Cascajosa"

Article Synopsis
  • Purpose of the Study
  • : The research aimed to investigate the changes in retinal microvasculature and sensitivity in patients with type 1 diabetes (T1D) before the onset of diabetic retinopathy (DR).
  • Methods and Findings
  • : In total, 62 eyes from 31 T1D patients (without DR and with mild DR) and 40 eyes from 20 healthy controls were examined using OCTA for vascular parameters and microperimetry for retinal sensitivity. No significant differences in retinal measurements were found between the T1D groups but notable differences were observed when compared to healthy controls.
  • Conclusions
  • : The study concluded that patients with T1D, even without DR
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Objective: To describe ocular hypertension cases after using a new aflibercept prefilled syringe and to assess the main characteristics of these eyes and their possible association with intraocular pressure (IOP) changes.

Methods: Case series. We reported all the cases of ocular hypertension following aflibercept prefilled syringes (PFS) treatment in our department between April 2021 and December 2023.

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Purpose: To provide data on the most frequent causes, main characteristics, management, and outcomes of pediatric choroidal neovascularization (CNV) in a major tertiary referral hospital for children, together with a review of the current literature.

Methods: Case series including children diagnosed with CNV between 2008 and 2023. Age, sex, date of diagnosis, CNV etiology, CNV localization, treatment with anti-vascular endothelial growth factor (VEGF), and ophthalmological examination data at diagnosis and after one year of follow-up were recorded.

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Purpose: This study aims to answer a key question: is MYO7A-inherited retinal dystrophy (MYO7A-IRD) a photoreceptor-first or retinal pigment epithelium-first disease? A second aim was to determine the most useful biomarkers to monitor disease progression in pediatric patients with Usher syndrome type 1B (USH1) secondary to MYO7A mutation.

Methods: Fifty-two eyes from 26 patients with genetically-confirmed MYO7A-IRD underwent swept-source optical coherence tomography (SS-OCT). Structural abnormalities were evaluated and correlated with follow-up time and best corrected visual acuity (BCVA).

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Objectives: To evaluate the effectiveness of the anterior segment optical coherence tomography (AS-OCT) for the screening of anterior uveitis in children diagnosed with juvenile idiopathic arthritis (JIA).

Methods: A cross-sectional, observational, non-randomised study was conducted in JIA patients younger than 18 years. All patients underwent anterior segment (AS-OCT) and macular OCT.

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